Science says that when you inhale helium, it displaces the oxygen already present in your body.
Girl dies after inhaling helium from birthday balloon
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Gas embolism as a potential cause of death by helium poisoning – Postmortem computed tomography changes in two cases of suicidal helium inhalation - ScienceDirect
President Biden's executive order could hurt production and spike the price of natural gas used in advanced medical tools and birthday balloons
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Embolism warning: 12-year-old girl suffers brain embolism after inhaling helium